RNA Details
Disease Name
atrial fibrillation
Tissue
heart
RNA Symbol
mir-4443
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
dual-luciferase reporter assay; etc.
Target
THBS1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Hsa-miR-4443 inhibits myocardial fibroblast proliferation by targeting THBS1 to regulate TGF-beta1/alpha-SMA/collagen signaling in atrial fibrillation
Year
2021
Function
Hsa-miR-4443 protected atrial fibrillation(AF) by targeting THBS1 and regulated TGF-beta/alfa-SMA/collagen pathway to inhibit HCFB proliferation and collagen synthesis.
RNA Details
Disease Name
atrial fibrillation
Tissue
heart
RNA Symbol
mir-4443
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
dual-luciferase reporter assay etc.
Target
THBS1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Hsa-miR-4443 inhibits myocardial fibroblast proliferation by targeting THBS1 to regulate TGF-beta1/alpha-SMA/collagen signaling in atrial fibrillation
Year
2021
Function
Hsa-miR-4443 protected atrial fibrillation(AF) by targeting THBS1 and regulated TGF-beta/alfa-SMA/collagen pathway to inhibit HCFB proliferation and collagen synthesis.